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Summary: This study investigated the response of Camelina sativa (L.) Crantz to the availability of N and water availability and their effect on photosynthesis and yield parameters. Plant height, root and shoot dry matter, root:shoot ratio, xylem pressure potential, yield components, photosynthetic parameters and instantaneous water-use efficiency were remarkably influenced by water and nitrogen supply. Results suggest that the regulative capacity of N supply on photosynthetic and plant growth response is significantly affected by soil water status and C. sativa is more sensitive to water deficit than N supply.